A structural basis for cellular senescence
نویسندگان
چکیده
منابع مشابه
A structural basis for cellular senescence
Replicative senescence (RS) that limits the proliferating potential of normal eukaryotic cells occurs either by a cell-division counting mechanism linked to telomere erosion or prematurely through induction by cell stressors such as oncogene hyper-activation. However, there is evidence that RS also occurs by a stochastic process that is independent of number of cell divisions or cellular stress...
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ژورنال
عنوان ژورنال: Aging
سال: 2009
ISSN: 1945-4589
DOI: 10.18632/aging.100074